Hope Ignited: New Alliance Forged to Combat Neurodegenerative Devastation

Fueling the Fight: Angelini Ventures injects crucial capital into Therini Bio, bolstering a $75 million war chest.
A Novel Weapon: Therini Bio pioneers THN391, targeting toxic fibrin to combat neuroinflammation in Alzheimer's and DME.
Clinical Advance: Fresh funding propels THN391 into vital Phase 1b trials, heralding a new era of treatment.

In the relentless global battle against the silent scourge of neurodegenerative diseases like Alzheimer's, a powerful new alliance has been forged. Angelini Ventures has announced a significant investment, joining a formidable syndicate of top-tier international healthcare investors to complete Therini Bio's monumental $75 million Series A financing round^{6, 8}. This crucial injection of capital is set to catapult Therini Bio's groundbreaking work, targeting the insidious role of toxic fibrin accumulation and vascular dysfunction that drives these devastating conditions^{1, 3, 4}.

Therini’s revolutionary lead candidate, THN391, a potential first-in-class monoclonal antibody, has already demonstrated promising well-tolerated results in Phase 1a trials, showcasing a clean hematological profile^{1, 3}. It’s meticulously engineered to selectively neutralize fibrin-mediated neuroinflammation in the brain and retina without dangerously interfering with essential blood clotting¹. With this substantial financial reinforcement, Therini Bio is poised to advance THN391 into pivotal Phase 1b studies for Alzheimer’s Disease (AD) and Diabetic Macular Edema (DME). The funds will also critically support the development of an innovative fibrin/VEGF bispecific antibody, further broadening the therapeutic assault on these complex diseases^{6, 8}. This venture signifies a blazing beacon of hope, pushing the frontiers of immunotherapy to reclaim cognitive and visual health. Angelini Ventures' commitment to disruptive BioTech is further detailed at www.angeliniventures.com.

Hope Ignited: New Alliance Forged to Combat Neurodegenerative Devastation

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